(https://www.wcrf.org . Display your data in Ensembl. The experimental protocol was approved by the Ethics Committee of the Universidad de La Frontera (approval n 06/2013). The FASTQ files obtained from sequencing were aligned . Briefly, the dissected tissue was homogenized in a hypotonic lysis solution and fixed in 1% formaldehyde for 10 minutes at room temperature . Mus musculus, a species of mouse, has been one of the five key model organisms sequenced since the beginnings of the Human Genome Project. In addition, six blocks of syntenically identical regions from the genome of Mus musculus were scanned. Almost all scaffold and contig data were non-ambiguous nucleotides (95.76%). Database searches were performed with both Sequest HT and Mascot (version 2.4.0) using the target-reverse Mus musculus Swissprot reference proteome with the hAPP and hPSEN1 amino acid sequences added (mutations included). Transposable elements (TEs, or mobile genetic elements, MGEs) are ubiquitous genetic elements that make up a substantial proportion of the genome of many species. 1. INTRODUCTION. Mus spretus: Characteristics: strain background: SPRET/EiJ tissue: cortex genotype: WT: Extracted molecule: genomic DNA: Extraction protocol: Hi-C (Jiang, et. Salient features of Mus musculus 1. 1. Genomes Pages - Mus musculus chromosome 5 . We assembled a large collection of Mus musculus data, independently developed nine different computational methods using these data to predict gene functions, and compared the predictive performance of each submission using held-out genes, a prospective evaluation, and a focused literature-based assessment of the top novel predictions. The reference genome will allow for experiments aimed at elucidating the mechanisms by which this widely distributed rodent serves as natural reservoir for several infectious diseases of public health importance, potentially enabling intervention strategies. These include: Mus musculus bactrianus (southwestern Asian house mouse), Mus musculus castaneus . 2008 Oct 15;582(23 . 3. Waterston RH, Lindblad-Toh K, Birney E, Rogers J, Abril JF, Agarwal P, Agarwala R, Ainscough R, Alexandersson M, An P, et al. A variety of inbred strains are available. Accession numbers of all the entries listed below may be downloaded as a text file for use in downloading using the Sequence Version Archive. S1 and Table S1).The genome sequences of 36 inbred laboratory mice were downloaded from the . Description Scientific Name Score Score Cover value Ident Len Accession v leptin precursor [Mus musculus] Mus musculus 305 305 . Home; Genomes. PLoS Biol. Fourteen clinically healthy male C57BL/6 mice (Mus musculus), five months old, were used. ): Cortical tissue was prepped for fluorescence activated nuclear sorting (FANS) as follows. 4. T number: T01002: Org_code: mmu: Name: Mus musculus (house mouse) Category: Reference genome: Annotation: yes: Taxonomy: TAX: 10090 Lineage: Eukaryota; Metazoa . Reference: PMID:17384582. A Biblioteca Virtual em Sade uma colecao de fontes de informacao cientfica e tcnica em sade organizada e armazenada em formato eletrnico nos pases da Regio Latino-Americana e do Caribe, acessveis de forma universal na Internet de modo compatvel com as bases internacionais. Download DNA sequence (FASTA) Convert your data to GRCm39 coordinates. The experiments were conducted according to the guidelines in the Guide for the Care and Use of Laboratory Animals . 5. NCBI RefSeq is the first resource to release an annotation for GRCm39, referred to as Mus musculus Annotation Release 109 . 2. Comprehensive summary statistics are provided in Table 2. The sequence of the mouse genome is a key informational tool for understanding the contents of the human genome and a key experimental tool for biomedical research. List of available genomes (on 5-MAY-2015) Description Length (bp) Sequence Proteins; Plain HTML; 1: Mus musculus 232000009773050 genomic scaffold genome shotgun . FVB_NJ_v3 Organism: Mus musculus (house mouse) Submitter: EMBL-EBI, WELLCOME . House mice are genetically diverse, yet their genetic background at the global level has not been fully understood. nationmal institute of genetics Abstract and Figures For more than 100 years, house mice (Mus musculus) have been used as a key animal model in biomedical research. We reasoned that observing a similar over-abundance of sequence in two matched regions, one from mouse and one from human . Most BioCyc compounds have been protonated to a reference pH value of 7.3. Authors: Grassmann R, Aboud M, Jeang KT. A second SNARE role for exocytic SNAP25 in endosome fusion. late 90s early 2000s electronic music. Matches 1 Rfam family (SSU_rRNA_eukarya, RF01960). We have provided confidence scores and estimates of . "Mus musculus", Wikipedia: The Free Encyclopedia 37 entries. The white-footed mouse . Random as well as directed mutagenesis is possible. The MDGA has been used to characterize and map the subspecific origin (from the three main Mus musculus subspecies; domesticus, musculus and castaneus) and haplotype diversity of SNPs for 198 samples including wild-caught mice, wild-derived laboratory strains and classical laboratory strains [ 23 ]. For more than 100 years, house mice ( Mus musculus) have been used as a key animal model in biomedical research. The reaction direction shown is in accordance with the Enzyme Commission rules (the physiological direction of the reaction, if known, is indicated by the arrow direction).. Mouse Genomes Project. Genome Project: PRJNA11785. Where two groups shared the same mass peak, we compared the strength of expression within the profile (expressed as a proportion of total central MUP output) either between two groups Name: Mus musculus (house mouse) Category: Reference genome . A huge pool of genetic data is available. Mus musculus (house mouse) The laboratory mouse is a major model organism for basic mammalian biology, human disease, and genome evolution. Reference Title: Reference Citation: 1. Annotated by 3 databases (ENA, RefSeq, SILVA). Size of the mouse is small when compared to the other animals, adding to ease of handling. The Mouse Genomes Project is an ongoing effort to catalog all forms of genetic variation between the common laboratory mouse strains and to construct and annotate reference genomes for the key strains. Taxonomy: The house mouse belongs to the Kingdom: Animalia, Phylum: Chordata, Class: Mammalia, Order: Rodentia, Family: Muridae, Subfamily: Murinae, Genus: Mus, Species: musculus [5]. al. List of available genomes (on 5-MAY-2015) Description Length (bp) Sequence Proteins; Plain HTML; 1: Mus musculus 232000009771200 genomic scaffold genome shotgun sequence (1 part in a CON entry) 38,912,783: CH466536 . Acc. To identify the genomic selection of domestication in classical inbred mice, we obtained samples from 36 wild mice for genome sequencing, including 11 samples of M. m. domesticus, 9 samples of M. m. musculus, and 16 samples of M. m. castaneus (Additional file 1: Fig. Reference: PMID:16155604. abstract & p.2 right column 3rd paragraph PubMed ID 19468303: Method "Using gene predictions for human and mouse from both NCBI [29] and Ensembl [30], [researchers] retained only those that were conserved either within or between the . Background. Il34 cDNA ORF clone, Mus musculus (house mouse) Gene Clones gRNAs The following Il34 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). Franois Bonhomme, Annie Orth, in Reference Module in Life Sciences, 2017. Search result files in .msf format w. Read more Contact Joseph Bundy, Florida State University College of Medicine GENOME: Mus musculus (house mouse) Help: Entry: T01002 Complete Genome : Org code: mmu. 24 entries. In the mouse reference assembly, sequences in the primary assembly unit (chromosomes and unlocalized and unplaced scaffolds) come from the C57BL/6J strain. 7. Mus spretus individuals had a greater proportion of introgression compared with M. m. domesticus, and within M. m. domesticus, the proportion . GRCm39 Genome Reference Consortium Mouse Build 39 Organism: Mus musculus (house mouse) Submitter: Genome Reference Consortium Date: 2020/06/24 Assembly type: Assembly level: Chromosome Genome representation: full RefSeq category: reference genome Synonyms: mm39 GenBank assembly accession: GCA_000001635.9 (latest) RefSeq assembly accession: GCF_000001635.27 (latest) IDs: 7358741[UID . Mus musculus is one of the most important model organisms in biology and medicine. 2009 May 5 7(5):e1000112. Mouse Mus musculus: Reference: Church et al, Lineage-specific biology revealed by a finished genome assembly of the mouse. Mus musculus (L) encompasses all the subspecies and geographical or chromosomal races of the house mouse. Accession numbers of all the entries listed below may be downloaded as a text file for use in downloading using the Sequence Version Archive. The complete mouse reference genome was sequenced in 2002. Despite the fact that these species show considerable intrinsic postzygotic reproductive isolation, introgression was observed in all individuals, including in the M. musculus reference genome (GRCm38). For several genomic regions that are variable between different strains, we provide alternate loci scaffolds comprised of clone-based sequences from a variety of other strains. Abstract. Human T-cell leukemia virus 1 infection - Mus musculus (house mouse) . Mass balance status: Balanced. Other reference assemblies Bar-On D, etal., FEBS Lett. House mice are genetically. Aikawa Y, etal., Mol Biol Cell. croatan beach webcam These sequences represent the protein coding region of the Il34 cDNA ORF which is encoded by the open reading frame (ORF) sequence. Samples and whole-genome sequencing. This was done for the entire length of the q-arm of HSA21, and for six blocks of 200 kb each elsewhere in the genome. Cells regulate TE expression against uncontrolled . Mice are biologically similar to humans and are thus good models for genetic diseases and research on the immune system. The recent growing interest in understanding the evolution and function of TEs has revealed that TEs play a dual role in genome evolution, development, disease, and drug resistance. 6. There have been a number of sub species of Mus musculus that have been described. A transgenic mouse can be created easily. Mus musculus strain B6CASTF1/J female postnatal (14 days) frontal cortex tissue: ENCBS511HRX: ENCLB594KVJ: 2: 1: Mus musculus strain B6CASTF1/J female postnatal (14 days) frontal cortex tissue: ENCBS589QKH: ENCLB681YXG No changes to the toolkit settings were implemented except for those necessary to use the mm10 build (GRCm38) of the Mus musculus genome. Human GRCh38/hg38; Human GRCh37/hg19; Human T2T-CHM13/hs1; Mouse GRCm39/mm39 Please see the PGDB Concepts Guide for more information. Searchable database of Paramyxoviridae genomes with visualization and analysis tools. 2. According to the World Cancer Research Fund, lung cancer is a disease that poses a significant healthcare burden world-wide. The Genome Data Viewer showing the annotation for the mouse pseudoautosomal region that includes annotations of four genes that were previously missing: Sts, Nlgn4l, Akap17a, and 2510022D24Rik. Genome assembly: GRCm39 (GCA_000001635.9) More information and statistics. The ability to manipulate the mouse genome, together with the wealth of disease models, inbred strains and genomic . Automated summary: This rRNA sequence is 1,870 nucleotides long and is found in Mus musculus. Imaging the assembly and disassembly kinetics of cis-SNARE complexes on native plasma membranes. Genome Project: PRJNA11785. Title: Molecular mechanisms of cellular . Title: Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation. 2006 May;17(5):2113-24. Wild populations of the house mouse ( Mus musculus) represent the raw genetic material for the classical inbred strains in biomedical research and are a major model system for evolutionary. Peromyscus leucopus is the major reservoir for several infectious diseases in North America. A_J_v3 Organism: Mus musculus (house mouse) Submitter: EMBL-EBI, WELLCOME TRUST GENOME CAMPUS, CAMBRIDGE Date: 2022/06/30 Assembly type: Assembly level: Chromosome Genome representation: full GenBank assembly accession: GCA_921998355.2 (latest) RefSeq assembly accession: n/a IDs: 13301041[UID] 34743838 [GenBank] 8. (from RefSeq NM_009029) (from RefSeq NM_009029) Gencode Transcript: ENSMUST00000022701.7 Description: Mus musculus RB transcriptional corepressor 1 (Rb1), mRNA. BLAST Descriptions Graphic Summary Alignments Taxonomy Sequences producing significant alignments Download Select columns * Show 100 v select all 3 sequences selected GenPept Graphics Distance tree of results Multiple alignment MSA Viewer Max Total Query E Per. Annotation . Journal: Nat Rev Cancer 7:270-80 (2007) DOI:10.1038/nrc2111. It is also the species which has paid the largest tribute to modern science, since the historical laboratory strains (the 'old inbreds') stem from this species through the old tradition of 'fancy . Its Binomial name is Mus musculus. Mus musculus (house mouse): Snap25 (synaptosomal-associated protein 25) . Authors: Matsuoka M, Jeang KT. Mus spicilegus genome and transcriptome raw read and base counts Open in new tab We produced a high quality genome of 2.50 Gbp with a scaffold N50 of 2.27 Mbp. GRCm38 Genome Reference Consortium Mouse Build 38 Organism: Mus musculus (house mouse) Submitter: Genome Reference Consortium Date: 2012/01/09 Assembly type: haploid-with-alt-loci Assembly level: Chromosome Genome representation: full Synonyms: mm10 GenBank assembly accession: GCA_000001635.2 (replaced) RefSeq assembly accession: GCF_000001635.20 (replaced) IDs: 327618[UID] 326478 [GenBank . Mus musculus 18S ribosomal RNA (Rn18s) sequence is a product of Rn18s gene. Epub 2006 Feb 15. It is a mammal. Mus cypriacus (Cypriot mouse) LinkOut; Mus famulus (servant mouse) LinkOut; Mus fragilicauda LinkOut; Mus gratus LinkOut; Mus lepidoides LinkOut; Mus macedonicus (Macedonian mouse) LinkOut; Mus musculus (house mouse) LinkOut BLAST page; Mus musculus domesticus x Mus spretus Mus musculus x Mus caroli Mus musculus x Mus spretus Has a conserved secondary structure or a structured region.
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